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De Quervain’s tendinitis occurs when the tendons around the base of the thumb become irritated or swollen, causing the synovium around the tendon to swell and changing the shape of the compartment, which makes it difficult for the tendons to move properly.

Dupuytren’s contracture is a thickening of the fibrous tissue layer underneath the skin of the palm and fingers. It is a painless condition and not dangerous, however, the thickening and tightening (contracture) of this fibrous tissue can cause the fingers to curl (flex).

Tendinitis occurs when a tendon becomes irritated, inflamed or swollen and causes the synovium around the tendon to swell, changing the shape of the tendon sheath compartment and making it difficult for the tendons to move properly. Tendinitis can cause pain and tenderness along the hand or wrist that is particularly noticeable when grasping or gripping, forming a fist, or turning the wrist.